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T O P I C R E V I E W
mklab2
Posted - 05/04/2013 : 12:54:23 AM I am trying to fit Hill equation
y=Vmax X^n/((K^n+X^n))
when n is >0, it is fitting fine,
but when n = -1 , or some number < 0, it can not fit. It shows:
"Fit did not converge - mutual dependency exists between parameters. You may have overparameterized the fitting function. Fixing one of them may eliminate this problem."
and give me a horizontal line Please help me , what is the problem with the fitting ? ( I did not change anything with the function)
1 L A T E S T R E P L I E S (Newest First)
Sam Fang
Posted - 05/06/2013 : 11:07:06 PM Origin's built-in Hill function has a constraint by default:
n > 0
You can remove the constraint if n<0 in NLFit dialog's Bounds tab as shown below.