Hi,
One option is as followings:
1) Add a new column.
2) In the new column, create a Set Column Values formula, the F(x) row, as:
mod(i,100)==0?derivative(col(B),1):0/0
Where B is the short name of your Y data column you want to take the derivative of and the 1 is the order of the derivative.
That will assign the derivative of column B for every 100th row to the new column.
Then plot that new column.
If you are using a Line or Line + Symbol plot, you will have to open the Plot Details dialog. At the page level in the dialog, select the Display tab and check "Connect lines across Missing Data".
See if that works for you.
Thanks,
Chris Drozdowski
Originlab Technical Support