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Screensize: 640 x 480 800 x 600 1024 x 768 1280 x 1024 UserName: Password: Anti-Spam Code: Format Mode: Basic  Help  Prompt  Format: Font Andale Mono Arial Arial Black Book Antiqua Century Gothic Comic Sans MS Courier New Georgia Impact Lucida Console Script MT Bold Stencil Tahoma Times New Roman Trebuchet MS Verdana   Size 1 2 3 4 5 6   Color Black Red Yellow Pink Green Orange Purple Blue Beige Brown Teal Navy Maroon LimeGreen Message: * HTML is OFF * Forum Code is ON Smilies [quote][i]Originally posted by coco19[/i] [br]Origin Ver. and Service Release (Select Help-->About Origin): Origin2016 Operating System: Windows Hello Origin friends, I have 6 peaks, A, B, C, D, E, F I would like to fit them each with a simple Gaussian (for example) in order to obtain the integrated area under the curve. I would like to do a least squares fit such that: total area of A + B + C = total area of D + E + F Is their a way of fitting them all simultaneously to match this constraint? Very grateful for any advice. [:)] Thanks, Chloe [/quote]   Check here to include your profile signature. Check here to subscribe to this topic.