| T O P I C R E V I E W |
| Eddy_Phy |
Posted - 10/02/2009 : 06:09:36 AM
Origin Ver 7.0, XP
I study the transport kinetic of the intestinal epithelium. My result quite similar to the others that they analyzed and fitted the results with Michaelis-Menten plus linear component.
I very young in the research and in this software. How can I analyzing and fitting the results with Michaelis-Menten plus linear component.
Eddy |
| 2 L A T E S T R E P L I E S (Newest First) |
| Eddy_Phy |
Posted - 10/07/2009 : 04:36:25 AM
Thanks,
But I already done by myself.
Equation is V = (Vmax*S) / (Km + S) + m*S
m is slope of linear component
My results showed the curvilinear function (hyperbola+linear function) of transport rate of the intestinal epithelium and substrate concentration.
So, the intestinal epithelium transport this substrate via both active (Saturable or hyperbola function) and passive (Non-saturable/linear function) mechanisms.
Ed. |
| greg |
Posted - 10/06/2009 : 5:03:52 PM
Basic equation ...
Independent : S
Dependent : V
Parameters : Vmax, Km
Definition : V = (Vmax * S) / (Km + S)
Not sure how you want to add linear component, but here is an example ..
Independent : S
Dependent : V
Parameters : Vmax, Km, offset, scale
Definition : V = offset + scale * ((Vmax * S) / (Km + S))
Follow the steps in the Help file to create the fitting function. |
|
|
