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 sigmoid curve vs. Boltzmann funciton (curve fit)
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tony_lincoln

USA
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Posted - 08/18/2009 :  01:29:09 AM  Show Profile  Edit Topic  Reply with Quote  View user's IP address  Delete Topic
Hi,

I have to use sigmoidal funciton to fit several curves, say, 3 curves. The sigmoidal funciton is: f(x) = 1/(1+exp(-k*x)). So after fitting, I will get k. After curve fitting, I just simply get the average of 3 k values. That is all.
But, in Origin, the sigmoidal fitting was finished by Boltzmann function, which is y = A2 + (A1-A2)/(1 + exp((x-x0)/dx)). So what is k, in this case?
I guess, 1/dx should be k. for example, if dx = 2.0, then k = 5. so I should use 1/dx of sigmoidal function as the k in sigmoidal. Then get the average of 3 k values.
Am I correct? sorry for this question, and your message is highly appreciated.
Thanks.
Tony

larry_lan

China
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Posted - 08/18/2009 :  02:53:11 AM  Show Profile  Edit Reply  Reply with Quote  View user's IP address  Delete Reply
Hi Tony:

The Slogistic1 function under Growth/Sigmoidal category looks more like the function you want.

In most cases, we add a horizontal offset for built-in functions, so you can see most of the function were defined like (x -x0), where x0 is the offset. If you dont want this parameter, you can Fix it. (If you use the boltzmann function, you should also fix A1, A2)

It's OK to calculate k from -1/dx, the value is same, but the Error is different (You can't compute the error by Kerr = -1/DXerr ). So I recommend you creating a user-defined fitting function for your case.

Thanks
Larry
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