About error estimates when curve fitting with OriginThis is an important point and anyone interested should read the exchange of
notes posted in April 97 in this discussion group. It was certainly
disappointing to see the same very low estimates of the errors of curve fitting
parameters come up in the newly released Origin 5. However, an e-mail exchange
I have had with Scott Bertrand about this issue has established that there is a
new (but undocumented) option in Origin 5.
If one chooses to use weighting (e.g. the oddly named instrumental option) and
then selects 'control' under 'options', a tick box brightens up and offers the
choice of using or not using 'chi-squared when calculating errors'
(incidentally, this is another example of the odd terminology that Origin
employs -- chi squared has a quite different meaning for most statisticians).
If this box is unticked (the default is that it is ticked) the error estimates
are now those given by Origin 3.5 and earlier. These estimates are very close
to those obtained on analysing the same data using CVFIT, a program which was
written by my colleague David Colquhoun and which is something of a gold
standard for curve fitting.
Scott Bertrand told me in his final e-mail that this feature would now be
documented and put on the Microcal/Origin web site though I haven't seen it
there - perhaps because I haven't looked in the right place. It is important
that it should be documented not least because people using Origin 3.7 through
5 (default settings) to analyse data with weighting may be working with
inappropriately optimistic estimates of the errors of their curve fitting
parameters.
Those interested should also look at the contribution to the discussion group
by David Colquhoun (posted April 21st, 1997).